Eco-Friendly, Simple, Fast, and Sensitive UPLC-MS/MS Method for Determination of Pexidartinib in Plasma and Its Application to Metabolic Stability

Pexidartinib is the first drug approved by the U.S. Food and Drug Administration specifically to treat the rare joint tumor tenosynovial giant cell tumor. In the current study, a validated, selective, and sensitive UPLC-MS/MS assay was developed for the quantitative determination of pexidartinib in...

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Principais autores:	Essam Ezzeldin, Muzaffar Iqbal, Yousif A. Asiri, Gamal A. E. Mostafa, Ahmed Y. A. Sayed
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-01-01
Serija:	Molecules
Teme:	UPLC-MS/MS pexidartinib tyrosine kinase inhibitor metabolic stability gifitinib
Online dostop:	https://www.mdpi.com/1420-3049/27/1/297
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