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Heterogeneity, Measurement, and Clinical Implications of Oxygenation, Cell Signaling, and Redox Biology in Glioblastoma and Adult Diffuse Gliomas, with Context from Other Brain Tumors

Tumor oxygenation is a key determinant of cancer biology and treatment response, correlating with angiogenesis, recurrence, and malignant progression. Hypoxia is a defining feature of glioblastoma (GBM) and adult diffuse gliomas, generating low-oxygen niches that promote invasion, stem-like states,...

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Principais autores: Arabinda Das, Julian E. Bailes, Ann Barlow, Daniil P. Aksenov
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-04-01
coleção:Antioxidants
Assuntos:
glioblastoma
glioma
hypoxia
oxygenation
redox signaling
cell signaling
Acesso em linha:https://www.mdpi.com/2076-3921/15/4/505
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