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A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis.

The formation of mature cells by blood stem cells is very well understood at the cellular level and we know many of the key transcription factors that control fate decisions. However, many upstream signalling and downstream effector processes are only partially understood. Genome wide association st...

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Bibliografiske detaljer
Principais autores: Ewa Bielczyk-Maczyńska, Jovana Serbanovic-Canic, Lauren Ferreira, Nicole Soranzo, Derek L Stemple, Willem H Ouwehand, Ana Cvejic
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-07-01
Serier:PLoS Genetics
Online adgang:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004450&type=printable
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