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A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis.

The formation of mature cells by blood stem cells is very well understood at the cellular level and we know many of the key transcription factors that control fate decisions. However, many upstream signalling and downstream effector processes are only partially understood. Genome wide association st...

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Principais autores: Ewa Bielczyk-Maczyńska, Jovana Serbanovic-Canic, Lauren Ferreira, Nicole Soranzo, Derek L Stemple, Willem H Ouwehand, Ana Cvejic
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Genetics
Acceso en liña:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004450&type=printable
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