Benchmarking computational methods for single-cell chromatin data analysis

Abstract Background Single-cell chromatin accessibility assays, such as scATAC-seq, are increasingly employed in individual and joint multi-omic profiling of single cells. As the accumulation of scATAC-seq and multi-omics datasets continue, challenges in analyzing such sparse, noisy, and high-dimens...

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Bibliografske podrobnosti

Principais autores:	Siyuan Luo, Pierre-Luc Germain, Mark D. Robinson, Ferdinand von Meyenn
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-08-01
Serija:	Genome Biology
Teme:	Benchmark ScATAC-seq Clustering Feature engineering Dimensional reduction
Online dostop:	https://doi.org/10.1186/s13059-024-03356-x
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