Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation

Atopic dermatitis (AD) is one of the most common inflammatory skin diseases with complex pathogenesis involving epidermal barrier dysfunction, skin microbiome abnormalities and type-2-skewed immune dysregulation. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor th...

Полное описание

Библиографические подробности

Главные авторы:	Zhao-Yuan Wang, Yu-Xin Zheng, Fan Xu, Ying-Zhe Cui, Xue-Yan Chen, Si-Qi Chen, Bing-Xi Yan, Yuan Zhou, Min Zheng, Xiao-Yong Man
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-11-01
Серии:	Frontiers in Immunology
Предметы:	atopic dermatitis DNCB keratinocytes stat3 TSLP
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273182/full
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