Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation

Atopic dermatitis (AD) is one of the most common inflammatory skin diseases with complex pathogenesis involving epidermal barrier dysfunction, skin microbiome abnormalities and type-2-skewed immune dysregulation. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor th...

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Auteurs principaux:	Zhao-Yuan Wang, Yu-Xin Zheng, Fan Xu, Ying-Zhe Cui, Xue-Yan Chen, Si-Qi Chen, Bing-Xi Yan, Yuan Zhou, Min Zheng, Xiao-Yong Man
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-11-01
Collection:	Frontiers in Immunology
Sujets:	atopic dermatitis DNCB keratinocytes stat3 TSLP
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273182/full
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