Role of epigenetics and the transcription factor Sp1 in the expression of the D prostanoid receptor 1 in human cartilage
D prostanoid receptor 1 (DP1), a prostaglandin D2 receptor, plays a central role in the modulation of inflammation and cartilage metabolism. We have previously shown that activation of DP1 signaling downregulated catabolic responses in cultured chondrocytes and was protective in mouse osteoarthritis...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2023-11-01
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| Colección: | Frontiers in Cell and Developmental Biology |
| Materias: | |
| Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fcell.2023.1256998/full |
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