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HIF‐1 Targeting Intervention Renders Protection From Alzheimer's‐Like Pathology in a Humanized Mice Model of HIV Infection

ABSTRACT HIV‐associated neurocognitive disorders (HAND) affect 30%–50% of individuals living with HIV on combination antiretroviral therapy, with Alzheimer ’s‐like pathology as a potent comorbidity of HAND. Our previous studies have implicated hypoxia‐inducible factor‐1 alpha (HIF‐1α) as a central r...

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Huvudupphov: Sudipta Ray, Mohit Kumar, Divya T. Chemparathy, Prasanta K. Dash, Susmita Sil
Materialtyp: Artigo
Språk:Inglês
Utgiven: Wiley 2025-11-01
Serie:Journal of Extracellular Vesicles
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Länkar:https://doi.org/10.1002/jev2.70191
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