HIF‐1 Targeting Intervention Renders Protection From Alzheimer's‐Like Pathology in a Humanized Mice Model of HIV Infection

ABSTRACT HIV‐associated neurocognitive disorders (HAND) affect 30%–50% of individuals living with HIV on combination antiretroviral therapy, with Alzheimer ’s‐like pathology as a potent comorbidity of HAND. Our previous studies have implicated hypoxia‐inducible factor‐1 alpha (HIF‐1α) as a central r...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Sudipta Ray, Mohit Kumar, Divya T. Chemparathy, Prasanta K. Dash, Susmita Sil
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Wiley 2025-11-01
Reeks:	Journal of Extracellular Vesicles
Onderwerpen:	ADEVs Alzheimer's‐like pathology HAND HIF‐1α synaptodegeneration
Online toegang:	https://doi.org/10.1002/jev2.70191
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!