Defining occult disease in glioblastoma using spectroscopic MRI: implications for clinical target volume delineation

Abstract Background Outcomes in glioblastoma are improved by surgical resection and adjuvant radiation (RT). In primary GBM (pGBM), large clinical target volume (CTV) margins typically cover occult invasion. In recurrent GBM (rGBM), RT often uses tiny CTV margins that likely omit occult invasion due...

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Egile Nagusiak:	Jonathan B. Bell, Sulaiman Sheriff, Mohammed Z. Goryawala, Kaylie Cullison, Gregory A. Azzam, Jessica Meshman, Matthew C. Abramowitz, Michael E. Ivan, Macarena I. de la Fuente, Eric A. Mellon
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2025-05-01
Saila:	Radiation Oncology
Gaiak:	Spectroscopic MRI Glioblastoma
Sarrera elektronikoa:	https://doi.org/10.1186/s13014-025-02666-z
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