Defining occult disease in glioblastoma using spectroscopic MRI: implications for clinical target volume delineation

Abstract Background Outcomes in glioblastoma are improved by surgical resection and adjuvant radiation (RT). In primary GBM (pGBM), large clinical target volume (CTV) margins typically cover occult invasion. In recurrent GBM (rGBM), RT often uses tiny CTV margins that likely omit occult invasion due...

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Hlavní autoři:	Jonathan B. Bell, Sulaiman Sheriff, Mohammed Z. Goryawala, Kaylie Cullison, Gregory A. Azzam, Jessica Meshman, Matthew C. Abramowitz, Michael E. Ivan, Macarena I. de la Fuente, Eric A. Mellon
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-05-01
Edice:	Radiation Oncology
Témata:	Spectroscopic MRI Glioblastoma
On-line přístup:	https://doi.org/10.1186/s13014-025-02666-z
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