Application of a physiologically based pharmacokinetic model in predicting captopril disposition in children with chronic kidney disease
Abstract Over the last several decades, angiotensin-converting enzyme inhibitors (ACEIs) have been a staple in the treatment of hypertension and renovascular disorders in children. One of the ACEIs, captopril, is projected to have all the benefits of traditional vasodilators. However, conducting cli...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2023-02-01
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| Series: | Scientific Reports |
| Acceso en liña: | https://doi.org/10.1038/s41598-023-29798-0 |
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