Armored IL15 or IL15 receptor adaptors enhance proliferation and anti-tumor activity of CD19-targeted CAR-NK cells

Abstract Objective To construct CD19-targeted chimeric antigen receptor natural killer (CAR-NK) cells armored with interleukin15 (IL15) or IL15 receptor-linker (RLI) and preliminarily validate their proliferative capacity and anti-tumor activity in vitro. Methods Natural killer cells (NK92 and N...

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Hlavní autoři:	YU Mengyuan, LIU Xiuying, ZHANG Xiaotian
Médium:	Artigo
Jazyk:	Chinês
Vydáno:	Editorial Office of Journal of Army Medical University 2025-12-01
Edice:	陆军军医大学学报
Témata:	chimeric antigen receptor nk cells interleukin 15 anti-tumor activity proliferation
On-line přístup:	https://aammt.tmmu.edu.cn/html/202507093.html
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