Pathophysiological and Pharmacological Characteristics of <i>KCNJ5</i> 157-159delITE Somatic Mutation in Aldosterone-Producing Adenomas

Mutated channelopathy could play important roles in the pathogenesis of aldosterone-producing adenoma (APA). In this study, we identified a somatic mutation, <i>KCNJ5</i> 157-159delITE, and reported its immunohistological, pathophysiological and pharmacological characteristics. We conducted patch-cl...

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Autors principals:	Kang-Yung Peng, Hung-Wei Liao, Jeff S. Chueh, Chien-Yuan Pan, Yen-Hung Lin, Yung-Ming Chen, Peng-Ying Chen, Chun-Lin Huang, Vin-Cent Wu
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-08-01
Col·lecció:	Biomedicines
Matèries:	Aldosterone producing adenoma <i>KCNJ5</i> 157-159delITE mutation primary aldosteronism
Accés en línia:	https://www.mdpi.com/2227-9059/9/8/1026
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