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Pathophysiological and Pharmacological Characteristics of <i>KCNJ5</i> 157-159delITE Somatic Mutation in Aldosterone-Producing Adenomas

Mutated channelopathy could play important roles in the pathogenesis of aldosterone-producing adenoma (APA). In this study, we identified a somatic mutation, <i>KCNJ5</i> 157-159delITE, and reported its immunohistological, pathophysiological and pharmacological characteristics. We conducted patch-cl...

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Huvudupphov: Kang-Yung Peng, Hung-Wei Liao, Jeff S. Chueh, Chien-Yuan Pan, Yen-Hung Lin, Yung-Ming Chen, Peng-Ying Chen, Chun-Lin Huang, Vin-Cent Wu
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2021-08-01
Serie:Biomedicines
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Länkar:https://www.mdpi.com/2227-9059/9/8/1026
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