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The Role of HPV Genotyping, Cytology, and Methylation in the Triage of High-Risk HPV-Positive Patients

<b>Background/Objectives</b>: This study evaluates the diagnostic performance of DNA methylation testing, alone and in combination with cervical cytology, for high-grade squamous intraepithelial lesion (HSIL) detection. <b>Methods</b>: A prospective study was conducted on 170 high-risk HPV (hr-HPV)-...

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Principais autores: Anastasia Mortaki, Athanasios Douligeris, Maria-Anastasia Daskalaki, Eleni-Sivylla Bikouvaraki, Eirini Louizou, George Daskalakis, Alexandros Rodolakis, Themos Grigoriadis, Kalliopi I Pappa
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-05-01
Serier:Biomedicines
Fag:
human papillomavirus
high-grade squamous intraepithelial lesions
DNA methylation
FAM19A4
hsa-miR124-2
cervical cytology
Online adgang:https://www.mdpi.com/2227-9059/13/5/1139
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