PAX1 methylation for triage of HR-HPV-positive women: a comparative analysis with cytology and HPV16/18 genotyping

Abstract Objective To evaluate PAX1 hypermethylation (PAX1 m ) as a triage strategy test for cervical intraepithelial neoplasia grade 3 or worse (CIN3+) in high-risk human papillomavirus (HR-HPV)-positive women versus liquid-based cytology (LBC) and HPV16/18 genotyping. Methods This prospective, dia...

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Principais autores:	Zhengjiao Tong, Saiping Mao, Hong Tao, Peng Gan, Hongtao Li, Xiaozhu Pei, Xing Fan
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-05-01
Series:	BMC Cancer
Assuntos:	Cervical cancer Colposcopy Triage strategy High-risk human papillomavirus PAX1 methylation
Acceso en liña:	https://doi.org/10.1186/s12885-026-16235-4
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