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Venetoclax Drives Significant Shifts in BIM and BCL-2 but not MCL-1 Gene Expression in a Mouse Model of Acute Lymphoblastic Leukemia

Background: T and B acute lymphoblastic leukemia (T, B-ALL) has seen improved survival rates with intensified chemotherapy, but therapy-resistant or refractory ALL remains a significant clinical challenge. This study examined the inhibitory effects of Venetoclax drug on the apoptosis gene to explore...

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Bibliografiske detaljer
Principais autores: Saeid Abroun, Kaveh Tari
Format: Artigo
Sprog:Inglês
Udgivet: Shiraz University of Medical Sciences 2026-01-01
Serier:Middle East Journal of Cancer
Fag:
Online adgang:https://mejc.sums.ac.ir/article_51226_9f92941d3ab42223365e67b87dfe2d0c.pdf
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