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Venetoclax Drives Significant Shifts in BIM and BCL-2 but not MCL-1 Gene Expression in a Mouse Model of Acute Lymphoblastic Leukemia

Background: T and B acute lymphoblastic leukemia (T, B-ALL) has seen improved survival rates with intensified chemotherapy, but therapy-resistant or refractory ALL remains a significant clinical challenge. This study examined the inhibitory effects of Venetoclax drug on the apoptosis gene to explore...

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書誌詳細
主要な著者: Saeid Abroun, Kaveh Tari
フォーマット: Artigo
言語:Inglês
出版事項: Shiraz University of Medical Sciences 2026-01-01
シリーズ:Middle East Journal of Cancer
主題:
オンライン・アクセス:https://mejc.sums.ac.ir/article_51226_9f92941d3ab42223365e67b87dfe2d0c.pdf
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