Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence.
Telomeres have the ability to adopt a lariat conformation and hence, engage in long and short distance intra-chromosome interactions. Budding yeast telomeres were proposed to fold back into subtelomeric regions, but a robust assay to quantitatively characterize this structure has been lacking. There...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2020-12-01
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| coleção: | PLoS Genetics |
| Acesso em linha: | https://doi.org/10.1371/journal.pgen.1008603 |
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