Immune activation and response dynamics of human iPSC‐derived macrophages in tuberculosis infection models

Abstract Objectives Tuberculosis (TB) remains a global health challenge, with current antibiotic therapies being limited by long treatments, side effects and multidrug‐resistant mycobacterial strains. In addition, Mycobacterium tuberculosis (Mtb), the main causative agent of TB, employs evasion mech...

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Detalhes bibliográficos

Principais autores:	Daniela Paasch, Hannah Schevel, Andrea Riehle, Bibiana Costa, Hassan Toufaili, Tabea Gehnen, Julia Dahlmann, Andreas Pavlou, Anna‐Lena Neehus, Ariane Hai Ha Nguyen, Erika Schiering, Theresa Buchegger, Jacinta Bustamante, Gesine Hansen, Ulrich Kalinke, Erich Gulbins, Heike Grassmé, Nico Lachmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-01-01
coleção:	Clinical & Translational Immunology
Assuntos:	induced pluripotent stem cells, cell therapy, mycobacterial infections macrophages tuberculosis
Acesso em linha:	https://doi.org/10.1002/cti2.70071
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