Immune activation and response dynamics of human iPSC‐derived macrophages in tuberculosis infection models

Abstract Objectives Tuberculosis (TB) remains a global health challenge, with current antibiotic therapies being limited by long treatments, side effects and multidrug‐resistant mycobacterial strains. In addition, Mycobacterium tuberculosis (Mtb), the main causative agent of TB, employs evasion mech...

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Hauptverfasser:	Daniela Paasch, Hannah Schevel, Andrea Riehle, Bibiana Costa, Hassan Toufaili, Tabea Gehnen, Julia Dahlmann, Andreas Pavlou, Anna‐Lena Neehus, Ariane Hai Ha Nguyen, Erika Schiering, Theresa Buchegger, Jacinta Bustamante, Gesine Hansen, Ulrich Kalinke, Erich Gulbins, Heike Grassmé, Nico Lachmann
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-01-01
Schriftenreihe:	Clinical & Translational Immunology
Schlagworte:	induced pluripotent stem cells, cell therapy, mycobacterial infections macrophages tuberculosis
Online-Zugang:	https://doi.org/10.1002/cti2.70071
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