Pharmacogenetic variations and clinical implications of actionable CYP2D6/CYP2C19 variants in Central Indian patients with common mental disorders

IntroductionGenetic polymorphisms in CYP2D6 and CYP2C19 significantly influence the metabolism, efficacy, and safety of antidepressant medications. Limited data exist on the prevalence of these actionable pharmacogenetic variants in the Central Indian population. This study aimed to determine the fr...

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Autori principali:	Santenna Chenchula, Atal Shubham, Rozatkar Abhijit, Tamonud Modak, Kohat Komal, Ratinder Jhaj, Singh Jitendra, Satyaprakash V., Sadasivam Balakrishnan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2025-11-01
Serie:	Frontiers in Pharmacology
Soggetti:	pharmacogenetics CYP2D6 CYP2C19 antidepressants common mental disorders indian population
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1697866/full
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