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Selisistat, a SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies
Sirtuins (SIRTs) are NAD+-dependent histone deacetylases, which play a key role in cancer progression; however, their prognostic values in breast cancer (BC) remain a subject of debate and controversy. Accumulative evidence suggests that each sirtuin possesses individual character, implicating its r...
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| Main Authors: | , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis Group
2025-12-01
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| 叢編: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| 主題: | |
| 在線閱讀: | https://www.tandfonline.com/doi/10.1080/14756366.2025.2458554 |
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