Third-trimester estradiol is associated with isolated maternal hypothyroxinemia and attenuated TSH–FT4 coupling: evidence from rats and human astrocytes
IntroductionIsolated maternal hypothyroxinemia (IMH), defined by low free thyroxine (FT4) with thyroid-stimulating hormone (TSH) within the reference range, is a clinically relevant thyroid phenotype in late pregnancy, when estradiol (E2) rises sharply. We tested whether third-trimester E2 is associ...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2026-04-01
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| シリーズ: | Frontiers in Endocrinology |
| 主題: | |
| オンライン・アクセス: | https://www.frontiersin.org/articles/10.3389/fendo.2026.1795855/full |
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