Tissue tropism and functional adaptation of the SARS-CoV-2 spike protein in a fatal case of COVID-19

ABSTRACT Systemic spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to extrapulmonary tissues has been observed following acute infections. Autopsy studies further indicate tissue-specific virus diversity, including in immune-privileged sites. Questions remain on the viral dynam...

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主要な著者:	Katherine E. E. Johnson, Sydney Stein, Rita Afriyie Boateng, Shilpi Jain, Sabrina C. Ramelli, Trevor Stantliff, Shelly Curran, Marcos J. Ramos-Benítez, Andrew P. Platt, Stephanie Banakis, Wei Wang, Stephen M. Hewitt, Christa Zerbe, Steven M. Holland, Elizabeth M. Kang, Manmeet Singh, Emmie de Wit, William A. Lauer, Eric C. Rouchka, Melissa Smith, Mehul S. Suthar, Daniel S. Chertow, Elodie Ghedin
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology 2025-11-01
シリーズ:	Journal of Virology
主題:	viral evolution viral intrahost diversity tissue tropism coronavirus
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/jvi.00857-25
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