RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia

Philadelphia chromosome-positive (Ph+) leukemia is a fatal hematological malignancy. Although standard treatments with tyrosine kinase inhibitors (TKIs) have achieved remarkable success in prolonging patient survival, intolerance, relapse, and TKI resistance remain serious issues for patients with P...

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Principais autores:	Mengya Zhao, Beiying Dai, Xiaodong Li, Yixin Zhang, Chun Qiao, Yaru Qin, Zhao Li, Qingmei Li, Shuzhen Wang, Yong Yang, Yijun Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	eLife Sciences Publications Ltd 2024-06-01
Serija:	eLife
Teme:	mouse human E. coli
Online dostop:	https://elifesciences.org/articles/88375
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