Impact of additional chromosomal aberrations and BCR-ABL kinase domain mutations on the response to nilotinib in Philadelphia chromosome-positive chronic myeloid leukemia

Background Additional chromosomal aberrations in Philadelphia chromosome-positive chronic myeloid leukemia are non-random and strongly associated with disease progression, but their prognostic impact and effect on treatment response is not clear. Point mutations in the BCR-ABL kinase domain are prob...

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Detalhes bibliográficos

Principais autores:	Theo D. Kim, Seval Türkmen, Michaela Schwarz, Gökben Koca, Hendrik Nogai, Christiane Bommer, Bernd Dörken, Peter Daniel, Philipp le Coutre
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2010-04-01
coleção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/5554
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