Natural splice variant of MHC class I cytoplasmic tail enhances dendritic cell-induced CD8+ T-cell responses and boosts anti-tumor immunity.

Dendritic cell (DC)-mediated presentation of MHC class I (MHC-I)/peptide complexes is a crucial first step in the priming of CTL responses, and the cytoplasmic tail of MHC-I plays an important role in modulating this process. Several species express a splice variant of the MHC-I tail that deletes ex...

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Главные авторы:	Tania G Rodríguez-Cruz, Shujuan Liu, Jahan S Khalili, Mayra Whittington, Minying Zhang, Willem Overwijk, Gregory Lizée
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2011-01-01
Серии:	PLoS ONE
Online-ссылка:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022939&type=printable
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