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Synthesis of Novel 1,4- Dihydropyridine Derivatives Bearing Biphenyl-2'-Tetrazole Substitution as Potential Dual Angiotensin II Receptors and Calcium Channel Blockers

Introduction: We report the synthesis of novel 1,4-dihydropyridine derivatives containing biphenyl-2'-tetrazole moieties. We hypothesized that merging the key structural elements present in an AT1 receptor antagonist with key structural elements in 1,4-dihydropyridine calcium channel blockers would...

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Principais autores: Javid Shahbazi Mojarrad, Zahra Zamani, Hossein Nazemiyeh, Saeed Ghasemi, Davoud Asgari
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2011-06-01
coleção:Advanced Pharmaceutical Bulletin
Assuntos:
1
4-Dihydropyridine
Biphenyl-2'-tetrazole
Angiotensin II Blocker
Calcium Channel blocker
Acesso em linha:http://apb.tbzmed.ac.ir/Portals/0/Archive/Vol1No1/1-asgari.pdf
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