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Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans

The decline in episodic memory (EM) performance is a hallmark of cognitive aging and an early clinical sign in Alzheimer’s disease (AD). In this study, we conducted an epigenome-wide association study (EWAS) using DNA methylation (DNAm) profiles from buccal and blood samples for cross-sectional (<i>...

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Principais autores: Yasmine Sommerer, Valerija Dobricic, Marcel Schilling, Olena Ohlei, David Bartrés-Faz, Gabriele Cattaneo, Ilja Demuth, Sandra Düzel, Sören Franzenburg, Janina Fuß, Ulman Lindenberger, Álvaro Pascual-Leone, Sanaz Sedghpour Sabet, Cristina Solé-Padullés, Josep M. Tormos, Valentin Max Vetter, Tanja Wesse, Andre Franke, Christina M. Lill, Lars Bertram
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-11-01
Serier:Biomedicines
Fag:
DNA methylation
CpG
epigenome-wide association study
EWAS
episodic memory
cross-sectional
Online adgang:https://www.mdpi.com/2227-9059/10/11/2798
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