Blockade of Cannabinoid CB1 Receptors in the Dorsal Periaqueductal Gray Unmasks the Antinociceptive Effect of Local Injections of Anandamide in Mice

Divergent results in pain management account for the growing number of studies aiming at elucidating the pharmacology of the endocannabinoid/endovanilloid anandamide (AEA) within several pain-related brain structures. For instance, the stimulation of both Transient Receptor Potential Vanilloid type...

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Autori principali:	Diego C. Mascarenhas, Karina S. Gomes, Tatiani Sorregotti, Ricardo L. Nunes-de-Souza
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2017-10-01
Serie:	Frontiers in Pharmacology
Soggetti:	vanilloid substrates cannabinoid substrates anandamide periaqueductal gray antinociception
Accesso online:	http://journal.frontiersin.org/article/10.3389/fphar.2017.00695/full
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