Personality-based intergenerational effects of prenatal THC exposure in an inherited mouse model of social dominance and submissiveness

Abstract This study examines how stress-coping phenotypes influence the effect of prenatal $$\:\varDelta\:$$ 9-tetrahydrocannabinol (THC) exposure (PTE) on selectively bred Dominant (Dom) and Submissive (Sub) mice offspring exhibiting stress resilience and vulnerability, respectively. Pregnant Dom a...

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Detalhes bibliográficos

Principais autores:	Mohamed Mari, Anastasia Bagaev, Debpali Sur, Beatriz G. S. Rocha, Dilorom Begmatova, Natalia Zemliana, Abdalla Bowirrat, Kenneth Blum, Panayotis K. Thanos, Natalya M. Kogan, Albert Pinhasov
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-08-01
coleção:	Scientific Reports
Assuntos:	THC Prenatal development Stress resilience Endocannabinoid system (ECS) Social behavior Dopaminergic system (DAs)
Acesso em linha:	https://doi.org/10.1038/s41598-025-15528-1
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