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Colon impairments and inflammation driven by an altered gut microbiota leads to social behavior deficits rescued by hyaluronic acid and celecoxib

Abstract Background The exact mechanisms linking the gut microbiota and social behavior are still under investigation. We aimed to explore the role of the gut microbiota in shaping social behavior deficits using selectively bred mice possessing dominant (Dom) or submissive (Sub) behavior features. S...

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Principais autores: Oryan Agranyoni, Debpali Sur, Sivan Amidror, Nuphar Shidlovsky, Anastasia Bagaev, Nissan Yissachar, Albert Pinhasov, Shiri Navon-Venezia
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-04-01
Series:BMC Medicine
Assuntos:
Social behavior
Gut microbiota
Colon mucin
Tregs
SCFAs
Gut permeability
Acceso en liña:https://doi.org/10.1186/s12916-024-03323-0
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