Treatment resistance to melanoma therapeutics on a single cell level

Abstract Therapy targeting the BRAF-MEK cascade created a treatment revolution for patients with BRAF mutant advanced melanoma. Unfortunately, 80% patients treated will progress by 5 years follow-up. Thus, it is imperative we study mechanisms of melanoma progression and therapeutic resistance. We cr...

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Autori principali:	Lijun Yao, Bradley A. Krasnick, Ye Bi, Sunantha Sethuraman, Simon Goedegebuure, Amila Weerasinghe, Chris Wetzel, Qingsong Gao, Abimbola Oyedeji, Jacqueline Mudd, Matthew A. Wyczalkowski, Michael Wendl, Li Ding, Ryan C. Fields
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2024-09-01
Serie:	Scientific Reports
Accesso online:	https://doi.org/10.1038/s41598-024-72255-9
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