Low-grade, systemic inflammation and the risk of perioperative neurocognitive disorders in an observational study of older adults

Abstract Aims The neuroinflammatory response to surgery may contribute to the pathogenesis of post-operative delirium (POD) and cognitive dysfunction (POCD), but whether inflammation before surgery enhances the risk of developing these conditions is unclear. Here, we investigate the relationship bet...

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Autori principali:	Insa Feinkohl, Daniel Hadzidiakos, Thomas B. Dschietzig, Jürgen Janke, Maria Heinrich, Arjen J.C. Slooter, Claudia Spies, Georg Winterer, Tobias Pischon
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-12-01
Serie:	Scientific Reports
Soggetti:	Ageing Inflammation Neuroepidemiology Postoperative delirium Postoperative cognitive dysfunction
Accesso online:	https://doi.org/10.1038/s41598-025-31986-z
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