Single-molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing
Abstract Epigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for detecting and characterizing diseases such as cancer. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This approach generated up to 200 million reads for a s...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2023-05-01
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| Serie: | Genome Medicine |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s13073-023-01178-3 |
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