Protocol for a multicentric open-label randomized controlled trial comparing low-dose (0.25 mg/kg) and standard-dose (0.75 mg/kg) primaquine for gametocytocidal efficacy and safety in Plasmodium falciparum malaria

Abstract Introduction World Health Organization (WHO) in 2010, recommended 0.75 mg/kg single dose primaquine for killing gametocytes after ruling out glucose-6-phosphate dehydrogenase (G6PD) deficiency. However, considering the practical feasibility of G6PD testing, WHO revised the recommendation in...

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Κύριοι συγγραφείς:	Payal Gulati, Richa Singhal, Apoorv Gupta, Anjali, Praveen Kumar Tripathi, Dewesh Kumar, Diamond Prakash Sinha, S. P. Singh, Khileshwar Singh, Rajendra Kumar Baharia, K. N. Bhatt, Ashvin H. Vasava, Amit Gamit, Manoj B. Patki, Waseem A. Malla, Lokesh Kori, Deepali Savargaonkar, Nibir Chakma, Daksh Parmar, Lenin Alagesan, Ritika Kashyap, Kuldeep Singh, Anup R. Anvikar, Praveen K. Bharti, Nitika Nitika
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2026-05-01
Σειρά:	Malaria Journal
Θέματα:	Primaquine Gametocyte clearance Plasmodium falciparum Efficacy Safety India
Διαθέσιμο Online:	https://doi.org/10.1186/s12936-026-05912-1
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