ANGPTL4 induces granulosa cells proliferation dysfunction in PCOS by regulating the immune microenvironment and WNT signaling pathway

Abstract Background Polycystic ovary syndrome (PCOS) is a common disorder affecting the reproductive, endocrine, and metabolic systems in women. Dysfunction of granulosa cells (GCs) and imbalance of the immune microenvironment are key pathological mechanisms underlying PCOS. Previous studies have sh...

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Detalhes bibliográficos

Principais autores:	Jiale Lv, Ningzhen Zhang, Xiaoping Yang, Shan Han, Zhi Li, Yanqiu Xie, Yuhua Shi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	Journal of Ovarian Research
Assuntos:	Polycystic ovary syndrome ANGPTL4 WNT/β-catenin signaling pathway Immune microenvironment Granulosa cells
Acesso em linha:	https://doi.org/10.1186/s13048-026-01969-3
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