A porcine reproductive and respiratory syndrome virus (PRRSV)-specific IgM as a novel adjuvant for an inactivated PRRSV vaccine improves protection efficiency and enhances cell-mediated immunity against heterologous PRRSV challenge

Abstract Current strategies for porcine reproductive and respiratory syndrome (PRRS) control are inadequate and mainly restricted to immunization using different PRRS virus (PPRSV) vaccines. Although there are no safety concerns, the poor performance of inactivated PRRSV vaccines has restricted thei...

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Главные авторы:	Rui Chen, Bing Liu, Xiangmei Zhang, Mengmeng Qin, Jianhui Dong, Guoqian Gu, Chunyan Wu, Jingyu Wang, Yuchen Nan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2022-08-01
Серии:	Veterinary Research
Предметы:	PRRSV inactivated PRRSV vaccine broadly neutralizing antibody monoclonal antibody IgM vaccine adjuvant
Online-ссылка:	https://doi.org/10.1186/s13567-022-01082-5
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