Detection of genome-wide methylation changes in bladder cancer by long-read sequencing of urinary DNA

Abstract Background Non-invasive urine tests for bladder cancer (BC) could reduce dependence on flexible cystoscopy for diagnosis and surveillance. Most recent developments in urine testing are based on targeted detection of genomic and/or epigenomic markers. We hypothesised that long-read whole-gen...

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Detalhes bibliográficos

Principais autores:	Anshita Goel, Benjamin J. Tura, Joanne D. Stockton, Nicholas Tovey, Luke Ames, Andrew D. Beggs, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Richard T. Bryan, Douglas G. Ward, Roland Arnold
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-08-01
Colecção:	Clinical Epigenetics
Assuntos:	Bladder cancer Methylation Long-read sequencing Nanopore Urine DNA
Acesso em linha:	https://doi.org/10.1186/s13148-025-01946-5
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