Detection of genome-wide methylation changes in bladder cancer by long-read sequencing of urinary DNA

Abstract Background Non-invasive urine tests for bladder cancer (BC) could reduce dependence on flexible cystoscopy for diagnosis and surveillance. Most recent developments in urine testing are based on targeted detection of genomic and/or epigenomic markers. We hypothesised that long-read whole-gen...

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Bibliografiska uppgifter

Huvudupphov:	Anshita Goel, Benjamin J. Tura, Joanne D. Stockton, Nicholas Tovey, Luke Ames, Andrew D. Beggs, Maurice P. Zeegers, Nicholas D. James, K. K. Cheng, Richard T. Bryan, Douglas G. Ward, Roland Arnold
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2025-08-01
Serie:	Clinical Epigenetics
Ämnen:	Bladder cancer Methylation Long-read sequencing Nanopore Urine DNA
Länkar:	https://doi.org/10.1186/s13148-025-01946-5
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