Blood DNA methylation signature of cognitive reserve moderates the association between CSF tau pathology and memory in prodromal Alzheimer's disease

Abstract INTRODUCTION Cognitive reserve (CR) reflects variability in cognitive adaptability that modifies the impact of Alzheimer's disease (AD) pathology on cognition. However, blood‐based biomarkers of CR have not been established in prodromal AD. We operationalized CR as memory reserve, defined b...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	David Lukacsovich, Juan I. Young, Lissette Gomez, Brian W. Kunkle, Zhixin Mao, Wei Zhang, X. Steven Chen, Deirdre M. O'Shea, Tatjana Rundek, Eden R. Martin, Lily Wang, for the Alzheimer's Disease Neuroimaging Initiative
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Wiley 2026-04-01
سلاسل:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
الموضوعات:	cognitive reserve DNA methylation CSF pTau181 mild cognitive impairment Alzheimer's Disease Neuroimaging Initiative ADNI
الوصول للمادة أونلاين:	https://doi.org/10.1002/trc2.70257
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!