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WASHC3 knockout disrupts mitochondrial protein homeostasis and energy metabolism in cardiomyocytes

IntroductionThe WASH complex regulates endosomal actin dynamics and vesicular trafficking and is essential for neuronal integrity and motor function. Although variants in WASHC4, WASHC5, and WASHC3 are linked to neurodevelopmental abnormalities, the role of WASHC3 beyond the nervous system, particul...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Sujin Kim, Deung-Dae Park, Amelia Glazier, Wolfgang Rottbauer, Steffen Just
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2026-02-01
Sraith:Frontiers in Cardiovascular Medicine
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fcvm.2026.1682381/full
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