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WASHC3 knockout disrupts mitochondrial protein homeostasis and energy metabolism in cardiomyocytes

IntroductionThe WASH complex regulates endosomal actin dynamics and vesicular trafficking and is essential for neuronal integrity and motor function. Although variants in WASHC4, WASHC5, and WASHC3 are linked to neurodevelopmental abnormalities, the role of WASHC3 beyond the nervous system, particul...

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Bibliografiske detaljer
Principais autores: Sujin Kim, Deung-Dae Park, Amelia Glazier, Wolfgang Rottbauer, Steffen Just
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-02-01
Serier:Frontiers in Cardiovascular Medicine
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fcvm.2026.1682381/full
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