MTDH Mediates Estrogen-Independent Growth and Tamoxifen Resistance by Down-Regulating PTEN in MCF-7 Breast Cancer Cells
Background: About 70% of human breast cancers express estrogen receptor α (ERα) and in this kind of breast cancer estrogen plays an important role. Estrogen independent growth has been reported to promote resistance to one of the selective estrogen receptor modulators (SERMs) tamoxifen which is clin...
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| Format: | Artigo |
| Sprache: | Inglês |
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Cell Physiol Biochem Press GmbH & Co KG
2014-05-01
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| Schriftenreihe: | Cellular Physiology and Biochemistry |
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| Online-Zugang: | http://www.karger.com/Article/FullText/358719 |
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