MTDH Mediates Estrogen-Independent Growth and Tamoxifen Resistance by Down-Regulating PTEN in MCF-7 Breast Cancer Cells

Background: About 70% of human breast cancers express estrogen receptor α (ERα) and in this kind of breast cancer estrogen plays an important role. Estrogen independent growth has been reported to promote resistance to one of the selective estrogen receptor modulators (SERMs) tamoxifen which is clin...

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Detalhes bibliográficos

Principais autores:	Chunyuan Xu, Xiaoli Kong, Haiji Wang, Ning Zhang, Xiangnan Kong, Xia Ding, Xiaoyan Li, Qifeng Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
coleção:	Cellular Physiology and Biochemistry
Assuntos:	MTDH Estrogen-independent growth Tamoxifen resistance PTEN Breast cancer
Acesso em linha:	http://www.karger.com/Article/FullText/358719
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