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Targeting ALDOA to modulate tumorigenesis and energy metabolism in retinoblastoma

Summary: This study aims to elucidate the pivotal role of aldolase A (ALDOA) in retinoblastoma (RB) and evaluate the potential of the ALDOA inhibitor itaconate in impeding RB progression. Utilizing single-cell RNA sequencing, ALDOA consistently exhibits overexpression across diverse cell types, part...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Yinghao Wang, Junjie Tang, Yaoming Liu, Zhihui Zhang, Hongwei Zhang, Yujun Ma, Xinyue Wang, Siming Ai, Yuxiang Mao, Ping Zhang, Shuxia Chen, Jinmiao Li, Yang Gao, Chao Cheng, Cheng Li, Shicai Su, Rong Lu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2024-09-01
Seri Bilgileri:iScience
Konular:
Molecular biology
Cancer
Transcriptomics
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2589004224019503
Etiketler: Etiketle
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