CCL5/RANTES signaling in inflammation dysregulation after mild traumatic brain injury

Abstract Background Mild traumatic brain injury (mTBI) is the most prevalent form of brain injury. Secondary damage following mTBI contributes to neuronal degeneration by promoting neuroinflammation, amyloid accumulation, and oxidative stress (OS). Microglia exhibit dual roles after injury, contribu...

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Principais autores:	Man-Hau Ho, Yih-Jeng Tsai, Yu-Hsuan Lee, Yi-Chen Hsieh, Chia-Hung Yen, Jia-Yi Wang, Thierry Burnouf, Chia-Yen Chen, Wen-Cheng Lin, Yun Wang, Yung-Hsiao Chiang, Barry J. Hoffer, Szu-Yi Chou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	Journal of Biomedical Science
Assuntos:	CCL5 CCR5 signaling Microglia Mild traumatic brain injury Oxidative stress
Acesso em linha:	https://doi.org/10.1186/s12929-025-01203-0
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